Optogenetics and deep brain stimulation neurotechnologies.

O10: Deep Brain Stimulation and Psychiatry

The use of deep brain stimulation in psychiatric disorders has received great interest owing to the small risk of the operation, the reversible nature of the technique, and the possibility of optimizing treatment postoperatively. Currently deep brain stimulation in psychiatry is investigated for obsessive-compulsive disorder, Gilles de la Tourette’s syndrome and major depression. This presentat...

Prospects for Optogenetic Augmentation of Brain Function

The ability to optically control neural activity opens up possibilities for the restoration of normal function following neurological disorders. The temporal precision, spatial resolution, and neuronal specificity that optogenetics offers is unequalled by other available methods, so will it be suitable for not only restoring but also extending brain function? As the first demonstrations of opti...

Control of epileptic seizures by electrical low frequency deep brain stimulation: A review of probable mechanisms

Epilepsy is the most common neurological disease with no definitive method in treatment. Notably, the main way to treat and control epileptic seizures is drug therapy. However, about 20-30% of patients with epilepsy are drug resistant and require other therapeutic manners. Deep brain stimulation is a new therapeutic strategy for these patients. Conspicuously, there are no clear answers for basi...

Deep Brain Stimulation and Gene Expression Alterations in Parkinson’s Disease

The Birth of Optogenetics | The Scientist

For a few years now, I’ve taught a course at MIT called “Principles of Neuroengineering.” The idea of the class is to get students thinking about how to create neurotechnology innovations—new inventions that can solve outstanding scientific questions or address unmet clinical needs. Designing neurotechnologies is difficult because of the complex properties of the brain: its inaccessibility, het...